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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.68 (2022) >
Please use this identifier to cite or link to this item:
http://ir.fmu.ac.jp/dspace/handle/123456789/1647
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| Title: | Plastic bronchitis associated with influenza B virus infection: A case report |
| Authors: | Shirota, Jun
Sato, Masatoki
Saito, Yasushi
Asano, Yuichiro
Tomita, Yoichi
Watanabe, Masahiro
Suyama, Kazuhide
Kawasaki, Yukihiko
Hosoya, Mitsuaki |
| Affiliation: | 小児科学講座 |
| Source title: | Fukushima Journal of Medical Science |
| Volume: | 68 |
| Issue: | 1 |
| Start page: | 43 |
| End page: | 48 |
| Issue Date: | 2022 |
| Abstract: | Plastic bronchitis (PB) is a severe acute respiratory disease that develops as a result of the formation of branching mucus plugs in the bronchial tree. PB is known as a complication of influenza A virus infection, but some cases have been associated with influenza B virus infections. This patient was a 3-year-old boy with no history of allergic disease who developed PB requiring ventilator management after influenza B virus infection. He was hospitalized and managed with ventilator support because of acute respiratory failure. Influenza B virus infection was diagnosed via rapid antigen test and real-time reverse-transcription polymerase chain reaction (RT-PCR). A bronchoscopy performed after a chest X-ray and computed tomography confirmed the presence of extensive atelectasis in the right lung field and mucus plugs in the right bronchus. The patient's respiratory condition improved rapidly after removal of the plugs. Quantitative real-time RT-PCR performed with nasal and aspirated sputum samples obtained at hospitalization revealed a higher viral RNA load in the upper rather than in the lower respiratory tract. Viral replication in the lower respiratory was not found to be a major contributor toward mucus plug formation. The finding of increased serum IgE in the absence of a history of allergic disease suggests that an allergic reaction contributed to the formation of mucus plugs. |
| Publisher: | The Fukushima Society of Medical Science |
| Publisher (Alternative foam): | 福島医学会 |
| language: | eng |
| URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/1647 |
| Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/1647/1/FksmJMedSci_68_p43.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2021-08 |
| PubMed ID: | 35314523 |
| Related Page: | https://doi.org/10.5387/fms.2021-08 |
| Rights: | © 2022 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| Rights: | https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| Appears in Collections: | Vol.68 (2022)
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