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Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/643

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Title: Efficacy of endoscopic ultrasound-guided fine-needle aspiration for schwannoma: six cases of a retrospective study
Authors: Takasumi, Mika
Hikichi, Takuto
Takagi, Tadayuki
Suzuki, Rei
Watanabe, Ko
Nakamura, Jun
Sugimoto, Mitsuru
Kikuchi, Hitomi
Konno, Naoki
Waragai, Yuichi
Asama, Hiroyuki
Obara, Katsutoshi
Ohira, Hiromasa
Affiliation: 消化器内科学講座
内視鏡診療部
消化器内視鏡先端医療支援講座
Source title: Fukushima Journal of Medical Science
Volume: 63
Issue: 2
Start page: 75
End page: 80
Issue Date: 2017
Abstract: BACKGROUND: Schwannomas are difficult to diagnose using imaging alone. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is an effective and safe tissue sampling technique. Nevertheless, few reports have described EUS-FNA for schwannoma. OBJECTIVE: This study evaluates the efficacy of EUS-FNA for diagnosing schwannoma. METHODS: This retrospective study examined six consecutive schwannoma patients who were diagnosed as having schwannoma either from EUS-FNA results or from surgically resected specimens. The primary endpoint was diagnostic accuracy of EUS-FNA for schwannoma. The secondary endpoint was EUS-FNA safety. RESULTS: Based on cytomorphologic features and immunocytochemistry results after EUS-FNA, 4 out of 6 patients (66.7%) were diagnosed with schwannoma. The diagnoses before EUS-FNA were the following: 3 cases of gastric subepithelial lesion (SEL, suspicious for gastrointestinal stromal tumor), 1 case of intraperitoneal tumor, 1 case of retroperitoneal tumor, and 1 case of pancreatic tumor, with sizes of 15-44 mm (median 36 mm). No case was diagnosed as schwannoma solely based on image findings. Two cases of gastric SELs could not be diagnosed as schwannoma by EUS-FNA before surgery. Inadequate sampling and a lack of additional material for immunohistochemical studies could have engendered less-definite diagnoses in those cases. No procedural adverse events occurred. CONCLUSION: The diagnostic accuracy rate of EUS-FNA for schwannoma is somewhat low. However, tissue samples were obtained safely using this method. Moreover, it is an important procedure for diagnosing schwannoma, which cannot be diagnosed solely from image findings.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/643
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/643/1/FksmJMedSci_63_p75.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.2015-21
PubMed ID: 28680005
Related Page: http://doi.org/10.5387/fms.2015-21
Rights: © 2017 The Fukushima Society of Medical Science
Appears in Collections:Vol.63 (2017)

Files in This Item:

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FksmJMedSci_63_p75.pdf1.58 MBAdobe PDFDownload

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