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Vol.63 (2017) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/639

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Title: Contrast-enhanced harmonic endoscopic ultrasonography in gallbladder cancer and pancreatic cancer
Authors: Sugimoto, Mitsuru
Takagi, Tadayuki
Suzuki, Rei
Konno, Naoki
Asama, Hiroyuki
Watanabe, Ko
Nakamura, Jun
Kikuchi, Hitomi
Waragai, Yuichi
Takasumi, Mika
Sato, Yuki
Hikichi, Takuto
Ohira, Hiromasa
Affiliation: 消化器内科学講座
内視鏡診療部
Source title: Fukushima Journal of Medical Science
Volume: 63
Issue: 2
Start page: 39
End page: 45
Issue Date: 2017
Abstract: Endoscopic ultrasonography (EUS) plays a major role in diagnosing gallbladder (GB) cancer and pancreatic cancer (PC). In cases of GB cancer, EUS allows for precise observations of morphology and wall layers. However, proficiency is required for the morphologic diagnosis of GB tumors. Therefore, contrast-enhanced harmonic EUS (CH-EUS) began to be performed to diagnose GB lesions. CH-EUS enables real-time observation of the hemodynamics of GB tumors. The enhanced patterns generated by CH-EUS improve precision in the diagnosis of such tumors.PC appears as a hypoechoic mass on EUS. However, distinguishing between PC and mass-forming pancreatitis or focal autoimmune pancreatitis (AIP) is difficult via conventional EUS. CH-EUS allows for differentiating among these diseases (PC is hypoenhanced and heterogeneously enhanced, pancreatitis is isoenhanced, and a pancreatic neuroendocrine tumor is hyperenhanced). EUS-guided fine needle aspiration (EUS-FNA) also contributes to pathological diagnoses of pancreatic lesions. However, certain PC patients cannot be diagnosed via EUS-FNA. PC is heterogeneously enhanced on CH-EUS, and unenhanced regions have been reported to be areas of fibrosis or necrosis. CH-EUS-guided fine needle aspiration (CH-EUS-FNA) permits puncturing of the enhanced area while avoiding necrotic and fibrotic regions. Moreover, as CH-EUS findings have been quantitatively analyzed, a time-intensity curve (TIC) has become usable for diagnosing solid pancreatic lesions. CH-EUS-related techniques have been developed and increasingly utilized in the pancreaticobiliary area.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/639
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/639/1/FksmJMedSci_63_p39.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.2017-04
PubMed ID: 28680009
Related Page: http://doi.org/10.5387/fms.2017-04
Rights: © 2017 The Fukushima Society of Medical Science
Appears in Collections:Vol.63 (2017)

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FksmJMedSci_63_p39.pdf624.69 kBAdobe PDFDownload

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