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Fukushima Journal of Medical Science >
Vol.60 (2014) >

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タイトル: Risk factors for left atrial thrombus from transesophageal echocardiography findings in ischemic stroke patients
著者: Kumagai, Tomohiro
Matsuura, Yutaka
Yamamoto, Teiji
Ugawa, Yoshikazu
Fukushima, Tetsuhito
学内所属: 神経内科学講座
衛生学・予防医学講座
誌名/書名: Fukushima Journal of Medical Science
巻: 60
号: 2
開始ページ: 154
終了ページ: 158
発行日: 2014年
抄録: Background: To identify the cause of cerebral embolism, we performed transesophageal echocardiography (TEE) in patients suspected of embolic brain infarction including transient ischemic attack (TIA). We analyzed TEE findings and investigated factors associated with left atrial thrombus (LAT) detected by TEE. Methods: We enrolled 98 consecutive patients who underwent TEE and had acute brain infarction or TIA that was possibly due to embolism. We assessed age, sex, presence of atrial fibrillation (AF), days from admission to TEE and TEE findings, including the prevalence of LAT, spontaneous echo contrast (SEC), left atrial appendage (LAA) slow flow velocity, patent foramen ovale (PFO), atrial septal aneurysm and aortic plaque (ASA). Results: LAT was detected with TEE in 20 patients (20%). The factors that were significantly associated with the presence of LAT were male sex (unadjusted odds ratio (OR), 3.94; 95% confidence interval (CI), 1.07-14.58; p=0.037), presence of AF (unadjusted OR, 9.58; 95% CI, 2.58-35.50; p< 0.001), SEC (unadjusted OR, 8.48; 95% CI, 2.57-28.00; p< 0.001) and LAA slow flow velocity (unadjusted OR, 5.18; 95% CI, 1.59-16.91; p=0.005). Multivariate logistic regression analysis revealed that male sex (adjusted OR, 5.30; 95% CI, 1.09-25.71; p=0.039), presence of AF (adjusted OR, 8.97; 95% CI, 1.10-73.20; p=0.041) and SEC (adjusted OR, 10.87; 95% CI, 1.001-118.0; p=0.049) were independently associated with LAT, but LAA slow flow velocity was not. Conclusion: SEC is an important risk factor associated with LAT in patients suspected of embolic brain infarction that is independent of AF.
出版者: The Fukushima Society of Medical Science
出版者(異表記): 福島医学会
本文の言語: eng
このページのURI: http://ir.fmu.ac.jp/dspace/handle/123456789/430
本文URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/430/1/FksmJMedSci_60_p154.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.2013-12
PubMed番号: 25747606
関連ページ: http://doi.org/10.5387/fms.2013-12
権利情報: © 2014 The Fukushima Society of Medical Science
出現コレクション:Vol.60 (2014)

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