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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.53 (2007) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/211
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| タイトル: | RETRACTED: Effects of olprinone on neuromuscular blockade caused by vecuronium |
| その他のタイトル: | Olprinone and vecuronium |
| 著者: | Katayama, Takaaki
Saitoh, Yuhji
Nemoto, Chiaki
Hirama, Takahiro
Isosu, Tsuyoshi
Murakawa, Masahiro |
| 学内所属: | 麻酔科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 53 |
| 号: | 2 |
| 開始ページ: | 61 |
| 終了ページ: | 69 |
| 発行日: | 2007年12月 |
| 抄録: | We studied the effect of olprinone on neuromuscular blockade caused by vecuronium. Thirty women undergoing nitrous oxide-oxygen-isoflurane anesthesia were randomly divided into olprinone (n=15) or control group (n=15). In the olprinone group, the patients received an intravenous initial loading dose of olprinone at a rate of 2 microg/kg/minute for 5 minutes, followed by a continuous infusion of olprinone at 0.3 microg/kg/minute. In the control group, the patients received normal saline. Thirty minutes after the beginning of the infusion of olprinone or normal saline, vecuronium (0.1 mg/kg) was administered. The degree of neuromuscular blockade was monitored electromyographically at the adductor pollicis muscle. The time to the onset of neuromuscular blockade, and to the return of the first, second, third, or fourth response in train-of-four (TOF; T1, T2, T3, or T4, respectively), and the time course of recovery of T1/control did not differ significantly between the groups. After 50-70 minutes of vecuronium, the TOF ratio (T4/T1) in the olprinone group was significantly higher than in the control group. During this period, the mean TOF ratios in the control and olprinone groups were 0.15-0.39 and 0.40-0.57, respectively. In conclusion, olprinone accelerates the recovery of the TOF ratio, and the quickening effect of olprinone on the recovery of the TOF ratio may be apparent 50-70 minutes after vecuronium in anesthetized patients receiving vecuronium. |
| 注記: | This article has been retracted. Retraction notice: Fukushima Journal of Medical Science. 2017; 63(2):126. 撤回論文 |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/211 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/211/3/FksmJMedSci_53_p61_RETRACTED.pdf |
| ISSN: | 0016-2590 |
| DOI: | 10.5387/fms.53.61 |
| PubMed番号: | 18402286 |
| 関連ページ: | https://doi.org/10.5387/fms.53.61 |
| 権利情報: | © 2007 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.53 (2007)
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