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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
A 医学部 = School of Medicine >
a10 学術雑誌論文 = Journal Article >
Please use this identifier to cite or link to this item:
http://ir.fmu.ac.jp/dspace/handle/123456789/129
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| Title: | Measurement of Optic Nerve Blood Flow During Dissection of Parasellar Tumors |
| Authors: | Aimi, Yuri
Saito, Kiyoshi
Nagatani, Tetsuya
Ito, Eiji
Watanabe, Tadashi
Wakabayashi, Toshihiko |
| Affiliation: | 脳神経外科学講座 |
| Source title: | Neurosurgical review |
| Volume: | 32 |
| Issue: | 2 |
| Start page: | 199 |
| End page: | 205 |
| Issue Date: | Apr-2009 |
| Publisher: | Springer |
| language: | eng |
| URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/129 |
| Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/129/1/NeurosurgRev_32_p199.pdf |
| ISSN: | 0344-5607
1437-2320 |
| DOI: | 10.1007/s10143-008-0176-y |
| PubMed ID: | 18853205 |
| Other version: | http://dx.doi.org/10.1007/s10143-008-0176-y |
| Rights: | © Springer-Verlag 2008. The original Publication is available at www.springerlink.com. |
| Abstract: | The authors describe direct measurement of optic nerve blood flow and examine application of such monitoring to detect optic nerve ischemia during parasellar tumor surgery. Twenty-six patients requiring surgery for parasellar tumors were evaluated prospectively. Ophthalmologic examination was performed before and after surgery. The optic nerve blood flow was measured using a laser Doppler flowmeter before tumor dissection (initial ONBF) and after tumor removal (final ONBF). The waveform was analyzed by a data acquisition system. In 16 patients, initial ONBF could be measured (22 nerves; 8.9±0.9 ml/100 g/min). Final ONBF could be determined in all 26 patients (42 nerves; 10.8±0.7 ml/100 g/min). In the 22 nerves with initial measurements, final ONBF (11.3±0.6 ml/100 g/min) was significantly increased (p<0.01). In 6 patients whose optic canal was unroofed, the optic nerve blood flow did not change immediately; nonetheless, an increase was prominent in the final phase (p<0.05). In another 6 patients, a small vessel adjacent to the optic nerve was temporarily occluded. The optic nerve blood flow was reduced demonstrably in 3 and recovered quickly after reperfusion. Intraoperative optic nerve blood flow measurement may be useful as a real-time monitoring for prediction and prevention of intraoperative optic nerve ischemia. |
| Appears in Collections: | a10 学術雑誌論文 = Journal Article
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