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Vol.60 (2014) >

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Title: Risk factors for left atrial thrombus from transesophageal echocardiography findings in ischemic stroke patients
Authors: Kumagai, Tomohiro
Matsuura, Yutaka
Yamamoto, Teiji
Ugawa, Yoshikazu
Fukushima, Tetsuhito
Affiliation: 神経内科学講座
Source title: Fukushima Journal of Medical Science
Volume: 60
Issue: 2
Start page: 154
End page: 158
Issue Date: 2014
Abstract: Background: To identify the cause of cerebral embolism, we performed transesophageal echocardiography (TEE) in patients suspected of embolic brain infarction including transient ischemic attack (TIA). We analyzed TEE findings and investigated factors associated with left atrial thrombus (LAT) detected by TEE. Methods: We enrolled 98 consecutive patients who underwent TEE and had acute brain infarction or TIA that was possibly due to embolism. We assessed age, sex, presence of atrial fibrillation (AF), days from admission to TEE and TEE findings, including the prevalence of LAT, spontaneous echo contrast (SEC), left atrial appendage (LAA) slow flow velocity, patent foramen ovale (PFO), atrial septal aneurysm and aortic plaque (ASA). Results: LAT was detected with TEE in 20 patients (20%). The factors that were significantly associated with the presence of LAT were male sex (unadjusted odds ratio (OR), 3.94; 95% confidence interval (CI), 1.07-14.58; p=0.037), presence of AF (unadjusted OR, 9.58; 95% CI, 2.58-35.50; p< 0.001), SEC (unadjusted OR, 8.48; 95% CI, 2.57-28.00; p< 0.001) and LAA slow flow velocity (unadjusted OR, 5.18; 95% CI, 1.59-16.91; p=0.005). Multivariate logistic regression analysis revealed that male sex (adjusted OR, 5.30; 95% CI, 1.09-25.71; p=0.039), presence of AF (adjusted OR, 8.97; 95% CI, 1.10-73.20; p=0.041) and SEC (adjusted OR, 10.87; 95% CI, 1.001-118.0; p=0.049) were independently associated with LAT, but LAA slow flow velocity was not. Conclusion: SEC is an important risk factor associated with LAT in patients suspected of embolic brain infarction that is independent of AF.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/430
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/430/1/FksmJMedSci_60_p154.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.2013-12
PubMed ID: 25747606
Related Page: http://doi.org/10.5387/fms.2013-12
Rights: © 2014 The Fukushima Society of Medical Science
Appears in Collections:Vol.60 (2014)

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FksmJMedSci_60_p154.pdf218.93 kBAdobe PDFDownload

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