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Vol.68 (2022) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/1876

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Title: Peripheral platelet phagocytosis in an extremely low birth weight infant: a case report
Authors: Hatanaka, Daisuke
Ito, Kana
Fukama, Eisuke
Nomura, Tomoaki
Kusakari, Michiko
Takahashi, Hidehiro
Nakamura, Toshihiko
Takahashi, Naoto
Source title: Fukushima Journal of Medical Science
Volume: 68
Issue: 2
Start page: 129
End page: 134
Issue Date: 2022
Abstract: A 768 g female neonate, born at 25 weeks' gestation, developed sepsis due to methicillin-resistant Staphylococcus epidermidis on day 14. Severe thrombocytopenia was observed, and hemophagocytic macrophages were identified in her peripheral blood smear. Cytokine profiles at the time of onset suggested that an inflammatory cytokine storm had activated lymphocytes and macrophages, leading to platelet phagocytosis. After administration of vancomycin for 14 days and immunoglobulin therapy, she improved without any complications. Considering the results of cytokine profiles, early intervention for infection may have prevented progression to hemophagocytic lymphohistiocytosis and reduced the severity of clinical symptoms.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/1876
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/1876/1/FksmJMedSci_68_p129.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.2022-03
PubMed ID: 35732414
Related Page: https://doi.org/10.5387/fms.2022-03
Rights: © 2022 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/
Appears in Collections:Vol.68 (2022)

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