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Vol.67 (2021) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/1625

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Title: Clinical course and background of nasopharyngeal antibiotic-resistant bacteria carriers among preschool children hospitalized for lower respiratory tract infection
Authors: Takeyama, Aya
Suzuki, Kenta
Ito, Masaki
Sato, Masatoki
Hashimoto, Koichi
Katayose, Masahiko
Hosoya, Mitsuaki
Affiliation: 小児科学講座
Source title: Fukushima Journal of Medical Science
Volume: 67
Issue: 3
Start page: 143
End page: 149
Issue Date: 2021
Abstract: Abstract We investigated the nasopharyngeal microbiota in preschool patients hospitalized with lower respiratory tract infection to clarify the relationships between culturable nasopharyngeal bacteria and prognosis. From 2016 to 2018, nasopharyngeal culture was performed on inpatients under 6 years of age with a lower respiratory tract infection. Among the 1,056 study patients, 1,046 provided nasopharyngeal samples that yielded positive cultures, yielding 1,676 isolated strains. Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, were isolated in 25%, 27%, and 31% of the samples, respectively, and were the major causes of respiratory tract infection in these children. The only factor associated with the isolation of antibiotic-resistant strains from the nasopharynx was daycare attendance, which did not affect clinical severity, such as duration of fever and hospitalization. This study demonstrated that resistant bacteria in the nasopharynx did not affect the severity of lower respiratory tract infection and supports the use of narrow-spectrum antimicrobial agents in accordance with published guidelines when initiating therapy for pediatric patients with community-acquired pneumonia.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/1625
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/1625/1/FksmJMedSci_67_p143.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.2021-07
PubMed ID: 34803081
Related Page: https://doi.org/10.5387/fms.2021-07
Rights: © 2021 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/
Appears in Collections:Vol.67 (2021)

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FksmJMedSci_67_p143.pdf259.38 kBAdobe PDFDownload

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