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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.67 (2021) >
Please use this identifier to cite or link to this item:
http://ir.fmu.ac.jp/dspace/handle/123456789/1378
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| Title: | Effects of daily alcohol intake on glomerular filtration rate over three years |
| Authors: | Sato, Yu
Yoshihisa, Akiomi
Maki, Takumi
Takeishi, Yasuchika |
| Affiliation: | 循環器内科学講座 |
| Source title: | Fukushima Journal of Medical Science |
| Volume: | 67 |
| Issue: | 1 |
| Start page: | 1 |
| End page: | 7 |
| Issue Date: | 2021 |
| Abstract: | Background: The association between daily alcohol intake and changes in renal function in the Japanese general population is not well established. Methods: We analyzed data from 150 residents who underwent specific health checkups held in Mishima Town in 2016 and 2019. We divided participants on the basis of alcohol consumption: residents with daily alcohol intake of < 20 g/day (the none-to-low group, n = 104, 69.3%); those with daily alcohol intake of ≥ 20 but < 40 g/day (the intermediate group, n = 30, 20.0%); and those with daily alcohol intake of ≥ 40 g/day (the high group, n = 16, 10.7%). We compared baseline characteristics. The primary endpoint was a decrease in estimated glomerular filtration rate (eGFR), defined as the decrease in eGFR greater than the median decrease over three years. Results: The three-year changes in eGFR were +0.3 (-4.8, +3.0), -2.3 (-5.1, +1.2), and -4.9 (-8.2, -2.9) mL/min/1.73 m2 in the none-to-low, intermediate, and high groups, respectively (P = 0.007). In the multivariate logistic regression analysis, a high amount of alcohol intake was independently associated with a decrease in eGFR, with adjusted odds ratio of 11.418 (95% confidence interval 1.554-83.879, P = 0.017). Conclusion: A high average daily alcohol intake is associated with a decrease in eGFR. |
| Publisher: | The Fukushima Society of Medical Science |
| Publisher (Alternative foam): | 福島医学会 |
| language: | eng |
| URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/1378 |
| Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/1378/1/FksmJMedSci_67_p1.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2020-20 |
| PubMed ID: | 33408305 |
| Related Page: | https://doi.org/10.5387/fms.2020-20 |
| Rights: | © 2021 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| Rights: | https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| Appears in Collections: | Vol.67 (2021)
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