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Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/129

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NeurosurgRev_32_p199.pdf1.73 MBAdobe PDFDownload
Title: Measurement of Optic Nerve Blood Flow During Dissection of Parasellar Tumors
Authors: Aimi, Yuri
Saito, Kiyoshi
Nagatani, Tetsuya
Ito, Eiji
Watanabe, Tadashi
Wakabayashi, Toshihiko
Affiliation: 脳神経外科学講座
Source title: Neurosurgical review
Volume: 32
Issue: 2
Start page: 199
End page: 205
Issue Date: Apr-2009
Abstract: The authors describe direct measurement of optic nerve blood flow and examine application of such monitoring to detect optic nerve ischemia during parasellar tumor surgery. Twenty-six patients requiring surgery for parasellar tumors were evaluated prospectively. Ophthalmologic examination was performed before and after surgery. The optic nerve blood flow was measured using a laser Doppler flowmeter before tumor dissection (initial ONBF) and after tumor removal (final ONBF). The waveform was analyzed by a data acquisition system. In 16 patients, initial ONBF could be measured (22 nerves; 8.9±0.9 ml/100 g/min). Final ONBF could be determined in all 26 patients (42 nerves; 10.8±0.7 ml/100 g/min). In the 22 nerves with initial measurements, final ONBF (11.3±0.6 ml/100 g/min) was significantly increased (p<0.01). In 6 patients whose optic canal was unroofed, the optic nerve blood flow did not change immediately; nonetheless, an increase was prominent in the final phase (p<0.05). In another 6 patients, a small vessel adjacent to the optic nerve was temporarily occluded. The optic nerve blood flow was reduced demonstrably in 3 and recovered quickly after reperfusion. Intraoperative optic nerve blood flow measurement may be useful as a real-time monitoring for prediction and prevention of intraoperative optic nerve ischemia.
Publisher: Springer
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/129
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/129/1/NeurosurgRev_32_p199.pdf
ISSN: 0344-5607
1437-2320
DOI: 10.1007/s10143-008-0176-y
PubMed ID: 18853205
Other version: http://dx.doi.org/10.1007/s10143-008-0176-y
Rights: © Springer-Verlag 2008. The original Publication is available at www.springerlink.com.
Appears in Collections:a10 学術雑誌論文等 = Journal Article

Files in This Item:

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NeurosurgRev_32_p199.pdf1.73 MBAdobe PDFDownload

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