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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
A 医学部 = School of Medicine >
a10 学術雑誌論文等 = Journal Article >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/129
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| タイトル: | Measurement of Optic Nerve Blood Flow During Dissection of Parasellar Tumors |
| 著者: | Aimi, Yuri
Saito, Kiyoshi
Nagatani, Tetsuya
Ito, Eiji
Watanabe, Tadashi
Wakabayashi, Toshihiko |
| 学内所属: | 脳神経外科学講座 |
| 誌名/書名: | Neurosurgical review |
| 巻: | 32 |
| 号: | 2 |
| 開始ページ: | 199 |
| 終了ページ: | 205 |
| 発行日: | 2009年4月 |
| 抄録: | The authors describe direct measurement of optic nerve blood flow and examine application of such monitoring to detect optic nerve ischemia during parasellar tumor surgery. Twenty-six patients requiring surgery for parasellar tumors were evaluated prospectively. Ophthalmologic examination was performed before and after surgery. The optic nerve blood flow was measured using a laser Doppler flowmeter before tumor dissection (initial ONBF) and after tumor removal (final ONBF). The waveform was analyzed by a data acquisition system. In 16 patients, initial ONBF could be measured (22 nerves; 8.9±0.9 ml/100 g/min). Final ONBF could be determined in all 26 patients (42 nerves; 10.8±0.7 ml/100 g/min). In the 22 nerves with initial measurements, final ONBF (11.3±0.6 ml/100 g/min) was significantly increased (p<0.01). In 6 patients whose optic canal was unroofed, the optic nerve blood flow did not change immediately; nonetheless, an increase was prominent in the final phase (p<0.05). In another 6 patients, a small vessel adjacent to the optic nerve was temporarily occluded. The optic nerve blood flow was reduced demonstrably in 3 and recovered quickly after reperfusion. Intraoperative optic nerve blood flow measurement may be useful as a real-time monitoring for prediction and prevention of intraoperative optic nerve ischemia. |
| 出版者: | Springer |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/129 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/129/1/NeurosurgRev_32_p199.pdf |
| ISSN: | 0344-5607
1437-2320 |
| DOI: | 10.1007/s10143-008-0176-y |
| PubMed番号: | 18853205 |
| 異版(出版者版等): | http://dx.doi.org/10.1007/s10143-008-0176-y |
| 権利情報: | © Springer-Verlag 2008. The original Publication is available at www.springerlink.com. |
| 出現コレクション: | a10 学術雑誌論文等 = Journal Article
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