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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.64 (2018) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/695
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| タイトル: | Feasibility of skin acetone analysis in patients with cardiovascular diseases |
| 著者: | Yokokawa, Tetsuro
Sato, Takamasa
Suzuki, Satoshi
Oikawa, Masayoshi
Yoshihisa, Akiomi
Kobayashi, Atsushi
Yamaki, Takayoshi
Kunii, Hiroyuki
Nakazato, Kazuhiko
Ishida, Takafumi
Takeishi, Yasuchika |
| 学内所属: | 循環器内科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 64 |
| 号: | 2 |
| 開始ページ: | 60 |
| 終了ページ: | 63 |
| 発行日: | 2018年 |
| 抄録: | Background: Breath acetone is reported to be a noninvasive biomarker for heart failure. However, the measurement of this metabolite requires expertize and is not standardized yet. Acetone is also released from the skin; thus, measuring acetone as a skin gas may be easier than breath analysis. Methods: We analyzed skin acetone collected from 41 hospitalized patients with cardiovascular diseases. Passive samplers were used to measure skin acetone emission. Passive sampler was softly fixed on the surface of forearm skin for 10 hour at night. Results: Skin acetone emission ranged from 0.00 to 2.70 ng/cm2/h, and was significantly correlated with blood ketone bodies (r = 0.377, p = 0.017). Conclusions: This is the first study to analyze skin gas in patients with cardiovascular diseases. Skin acetone emission was found to reflect blood ketone bodies. It is feasible to measure skin acetone emission for reflecting blood ketone bodies in patients with cardiovascular diseases. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/695 |
| 本文URL: | https://ir.fmu.ac.jp/dspace/bitstream/123456789/695/1/FksmJMedSci_64_p60.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2018-03 |
| PubMed番号: | 30012937 |
| 関連ページ: | https://doi.org/10.5387/fms.2018-03 |
| 権利情報: | © 2018 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.64 (2018)
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