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Vol.64 (2018) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/676

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Title: Comparison of surgical outcomes after pneumonectomy and pulmonary function-preserving surgery for non-small cell lung cancer
Authors: Higuchi, Mitsunori
Takagi, Hironori
Ozaki, Yuki
Inoue, Takuya
Watanabe, Yuzuru
Yamaura, Takumi
Fukuhara, Mitsuro
Muto, Satoshi
Okabe, Naoyuki
Matsumura, Yuki
Hasegawa, Takeo
Osugi, Jun
Hoshino, Mika
Shio, Yutaka
Suzuki, Hiroyuki
Affiliation: 会津医療センター外科学講座
呼吸器外科学講座
Source title: Fukushima Journal of Medical Science
Volume: 64
Issue: 1
Start page: 30
End page: 37
Issue Date: 2018
Abstract: Background: According to previous reports, lobectomy with bronchoplasty or angioplasty is a more feasible surgery than pneumonectomy for central-type non-small cell lung cancer. However, few studies have compared both the short- and long-term outcomes between pneumonectomy and pulmonary function-preserving surgery. Methods: From January 2004 to December 2015, 18 patients underwent pneumonectomy (Group PN) and 12 patients underwent pulmonary function-preserving surgery (group PS) at Fukushima Medical University Hospital. Clinicopathological factors were statistically compared between the two groups. Results: The operation times in Group PN and Group PS were 285.9±27.9 and 271.3±99.2 min, respectively (p=0.613), while the amounts of intraoperative bleeding were 324.8±248.9 and 164.5±116.6 g, respectively (p=0.020). The duration of chest drainage and hospitalization after surgery in both groups were not significantly different but there was a tendency toward shorter periods of these durations in Group PS. The 5-year disease-free survival (DFS) rate in Group PN and PS was 51.4% and 74.1%, respectively, without a significant difference (p=0.298). The 5-year overall survival (OS) rate in Group PN and PS was 52.5% and 56.6%, respectively, also without a significant difference (p=0.748). The 5-year OS rate was inferior to the 5-year DFS rate in Group PS, and the 5-year OS rate was not better than the 5-year DFS rate in Group PN. Conclusions: The short-term results were better in Group PS than PN. However, the long-term results in both groups were similar. Other causes of death influenced OS in both groups; this result might have been affected by the surgical procedures.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/676
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/676/1/FksmJMedSci_64_p30.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.2017-10
PubMed ID: 29459574
Related Page: https://doi.org/10.5387/fms.2017-10
Rights: © 2018 The Fukushima Society of Medical Science
Appears in Collections:Vol.64 (2018)

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FksmJMedSci_64_p30.pdf249.2 kBAdobe PDFDownload

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