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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.61 (2015) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/495
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| タイトル: | Clinical application of L-menthol in the upper gastrointestinal endoscopic procedure |
| 著者: | Kikuchi, Hitomi
Hikichi, Takuto
Takagi, Tadayuki
Suzuki, Rei
Watanabe, Ko
Nakamura, Jun
Sugimoto, Mitsuru
Waragai, Yuichi
Konno, Naoki
Asama, Hiroyuki
Takasumi, Mika
Watanabe, Hiroshi
Obara, Katsutoshi
Ohira, Hiromasa |
| 学内所属: | 消化器・リウマチ膠原病内科学講座
内視鏡診療部
消化器内視鏡先端医療支援講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 61 |
| 号: | 2 |
| 開始ページ: | 160 |
| 終了ページ: | 166 |
| 発行日: | 2015年 |
| 抄録: | Aim: Peppermint oil, which suppresses gastric peristalsis during esophagogastroduodenoscopy (EGD), is effective for determining the margin of a gastric tumor. This study was conducted to evaluate the utility of an L-menthol preparation for suppressing gastric peristalsis and for diagnosing gastric tumors. Methods: The study examined 124 patients who underwent EGD between January and April 2012. After 20 mL of 0.8% L-menthol was sprayed directly onto the mucosal surface of the gastric antrum, the degree of peristalsis suppression in the antrum was evaluated. The effectiveness of L-menthol for identifying new gastric tumors and determining tumor margins was also evaluated. Results: Gastric peristalsis was suppressed in 88.5% (69/78) of patients, with complete suppression of peristalsis achieved in 78.2%. L-menthol exerted a higher peristalsis-suppressive effect in patients with endoscopic gastric mucosal atrophy (93.3%, 56/60) than in patients without atrophy (72.2%, 13/18) (p = .014). L-menthol application caused the detection of new gastric tumors in 1.6% (2/124) of patients and clarification of the margin of three lesions (in 3 patients) identified as having an unclear margin before L-menthol application. Conclusion: These results suggest that L-menthol is effective for suppressing gastric peristalsis during EGD and suggest that it is useful for identifying gastric tumors and for determining tumor margins. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/495 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/495/1/FksmJMedSci_61_p160.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2015-18 |
| PubMed番号: | 26632191 |
| 関連ページ: | http://doi.org/10.5387/fms.2015-18 |
| 権利情報: | © 2015 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.61 (2015)
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