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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.60 (2014) >
Please use this identifier to cite or link to this item:
http://ir.fmu.ac.jp/dspace/handle/123456789/433
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| Title: | Four-year follow-up of pregnancy-associated osteoporosis: a case report |
| Authors: | Takahashi, Naoto
Arai, Itaru
Kayama, Satoru
Ichiji, Kenji
Fukuda, Hironari
Handa, Jun-Ichi
Konno, Shin-Ichi |
| Affiliation: | 整形外科学講座 |
| Source title: | Fukushima Journal of Medical Science |
| Volume: | 60 |
| Issue: | 2 |
| Start page: | 175 |
| End page: | 180 |
| Issue Date: | 2014 |
| Abstract: | A 22-year-old woman presented with complaints of severe pain in a wide region of the thoracolumbar spine. She developed severe pain in the thoracolumbar spine region 2 months after her first delivery and was referred 1 month later. A lateral thoracic X-ray showed depressed degenerative vertebrae (T7, T9). One month after the initial examination, thoracic sagittal magnetic resonance imaging showed low intensity areas on T1-weighted imaging and iso-high intensity areas on T2-weighted imaging at T5, 7, 8, 9 and 11. Bone mineral density measured by ultrasound was low (%YAM 76%). The bone metabolic markers were high, suggesting accelerated osteoclast activity. These findings prompted a diagnosis of pregnancy-associated osteoporosis. She was asked to stop breastfeeding and to wear a lumbar brace, and treatment with nutritional calcium, activated vitamin D3, and risedronate sodium was started. Her low back pain almost disappeared after treatment. Bone metabolic markers showed normalization 8 months after the initial examination. Risedronate sodium was stopped 2 years and 2 months after the initial examination. Teriparatide treatment was started because her bone mineral density remained low; however, the osteoblast marker P1NP was not increased 5 months after the start of teriparatide treatment. |
| Publisher: | The Fukushima Society of Medical Science |
| Publisher (Alternative foam): | 福島医学会 |
| language: | eng |
| URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/433 |
| Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/433/1/FksmJMedSci_60_p175.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2014-14 |
| PubMed ID: | 25283976 |
| Related Page: | http://doi.org/10.5387/fms.2014-14 |
| Rights: | © 2014 The Fukushima Society of Medical Science |
| Appears in Collections: | Vol.60 (2014)
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