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Vol.60 (2014) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/433

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Title: Four-year follow-up of pregnancy-associated osteoporosis: a case report
Authors: Takahashi, Naoto
Arai, Itaru
Kayama, Satoru
Ichiji, Kenji
Fukuda, Hironari
Handa, Jun-Ichi
Konno, Shin-Ichi
Affiliation: 整形外科学講座
Source title: Fukushima Journal of Medical Science
Volume: 60
Issue: 2
Start page: 175
End page: 180
Issue Date: 2014
Abstract: A 22-year-old woman presented with complaints of severe pain in a wide region of the thoracolumbar spine. She developed severe pain in the thoracolumbar spine region 2 months after her first delivery and was referred 1 month later. A lateral thoracic X-ray showed depressed degenerative vertebrae (T7, T9). One month after the initial examination, thoracic sagittal magnetic resonance imaging showed low intensity areas on T1-weighted imaging and iso-high intensity areas on T2-weighted imaging at T5, 7, 8, 9 and 11. Bone mineral density measured by ultrasound was low (%YAM 76%). The bone metabolic markers were high, suggesting accelerated osteoclast activity. These findings prompted a diagnosis of pregnancy-associated osteoporosis. She was asked to stop breastfeeding and to wear a lumbar brace, and treatment with nutritional calcium, activated vitamin D3, and risedronate sodium was started. Her low back pain almost disappeared after treatment. Bone metabolic markers showed normalization 8 months after the initial examination. Risedronate sodium was stopped 2 years and 2 months after the initial examination. Teriparatide treatment was started because her bone mineral density remained low; however, the osteoblast marker P1NP was not increased 5 months after the start of teriparatide treatment.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/433
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/433/1/FksmJMedSci_60_p175.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.2014-14
PubMed ID: 25283976
Related Page: http://doi.org/10.5387/fms.2014-14
Rights: © 2014 The Fukushima Society of Medical Science
Appears in Collections:Vol.60 (2014)

Files in This Item:

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FksmJMedSci_60_p175.pdf737.94 kBAdobe PDFDownload

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