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Vol.60 (2014) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/424

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Title: Tactile sensor is useful for estimating liver hardness and liver fibrosis compared with ultrasonography and computed tomography
Authors: Suzuki, Satoshi
Watanabe, Yohei
Yazawa, Takashi
Ishigame, Teruhide
Sassa, Motoki
Monma, Tomoyuki
Takawa, Tadashi
Kumamoto, Kensuke
Nakamura, Izumi
Ohoki, Shinji
Hatakeyama, Yuichi
Sakuma, Hiroshi
Ono, Toshiyuki
Omata, Sadao
Takenoshita, Seiichi
Affiliation: 器官制御外科学講座
Source title: Fukushima Journal of Medical Science
Volume: 60
Issue: 2
Start page: 116
End page: 122
Issue Date: 2014
Abstract: Background/Aims: We examined whether conventional ultrasonography (US) and computed tomography (CT) were useful to evaluate liver hardness and hepatic fibrosis by comparing the results with those obtained by a tactile sensor using rats with liver fibrosis. Methodology: We used 44 Wistar rats in which liver fibrosis was induced by intraperitoneal administration of thioacetamide. The CT and US values of each liver were measured before laparotomy. After laparotomy, a tactile sensor was used to measure liver hardness. We prepared Azan stained sections of each excised liver specimen and calculated the degree of liver fibrosis (HFI: hepatic fibrosis index) by computed color image analysis. Results: The stiffness values and HFI showed a positive correlation (r=0.690, p<0.001), as did the tactile values and HFI (r=0.709, p<0.001).In addition, the stiffness and tactile values correlated positively with each other (r=0.814, p<0.001). There was no correlation between the CT values and HFI, as well as no correlation between the US values and HFI. Conclusion: We confirmed that it was difficult to evaluate liver hardness and HFI by CT or US examination, and considered that, at present, a tactile sensor is useful method for evaluating HFI.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/424
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/424/1/FksmJMedSci_60_p116.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.2013-7
PubMed ID: 25283979
Related Page: http://doi.org/10.5387/fms.2013-7
Rights: © 2014 The Fukushima Society of Medical Science
Appears in Collections:Vol.60 (2014)

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FksmJMedSci_60_p116.pdf1.15 MBAdobe PDFDownload

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