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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.60 (2014) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/405
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| タイトル: | Oral rabeprazole administration on a procedure day suppresses bleeding after endoscopic submucosal dissection for gastric neoplasms |
| 著者: | Hikichi, Takuto
Sato, Masaki
Watanabe, Ko
Nakamura, Jun
Takagi, Tadayuki
Suzuki, Rei
Sugimoto, Mitsuru
Waragai, Yuichi
Kikuchi, Hitomi
Konno, Naoki
Ohira, Hiromasa
Obara, Katsutoshi |
| 学内所属: | 内視鏡診療部
消化器・リウマチ膠原病内科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 60 |
| 号: | 1 |
| 開始ページ: | 68 |
| 終了ページ: | 74 |
| 発行日: | 2014年8月8日 |
| 抄録: | [Aim] The efficacy of pre-procedure oral proton pump inhibitor (PPI) administration for gastric endoscopic submucosal dissection (ESD) is unclear. This study evaluated oral PPI administration effectiveness on the day of ESD to prevent post-ESD bleeding. [Methods] This study examined 55 patients who underwent ESD for gastric neoplasm. Group A comprised 31 patients who took rabeprazole sodium (RPZ) 20 mg/day beginning 7-8 hr before ESD. Group B comprised 24 who took RPZ 20 mg/day beginning three days before ESD. Gastric pH (G-pH) was measured at one month before ESD (pre-ESD pH), immediately before ESD (ESD pH), and seven days after ESD (post-ESD pH). The post-ESD bleeding rate and changes in G-pH were recorded. [Results] No significant difference in post-ESD bleeding rates was found (Group A 3.2%, Group B 0%). ESD pH and post-ESD pH were significantly higher than pre-ESD pH in both groups (P<0.001). The ESD pH for Group A was higher than 6 (6.5±1.1), providing hemostasis for intragastric bleeding. [Conclusions] Oral RPZ administration on the day of gastric ESD can suppress post-ESD bleeding equivalently to administration three days before ESD. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/405 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/405/1/FksmJMedSci_60_p68.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2013-17 |
| PubMed番号: | 25030714 |
| 関連ページ: | http://dx.doi.org/10.5387/fms.2013-17 |
| 権利情報: | © 2014 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.60 (2014)
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