福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.59 (2013) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/371
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タイトル: | Heavy metals in blood and urine and its relation to depressive symptoms in Parkinson's disease patients |
著者: | Fukushima, Tetsuhito Tan, Xiaodong Luo, Yunwen Wang, Puqing Song, Jinhui Kanda, Hideyuki Hayakawa, Takehito Kumagai, Tomohiro Kakamu, Takeyasu Tsuji, Masayoshi Hidaka, Tomoo Mori, Yayoi |
学内所属: | 衛生学・予防医学講座 |
誌名/書名: | Fukushima Journal of Medical Science |
巻: | 59 |
号: | 2 |
開始ページ: | 76 |
終了ページ: | 80 |
発行日: | 2013年 |
抄録: | Objectives Some heavy metals are suspected to be pathogenic to both Parkinson's disease (PD) and depression. Common background may exist in them. Methods Subjects comprised PD patients with depression, PD patients without depression and controls recruited from the outpatient clinic in China. Morning blood and urine samples were used to measure concentrations of metals and vitamins. Results Whole-blood manganese was significantly higher in the PD patients without depression than in both the PD patients with depression and the controls. Serum iron was significantly higher in the PD patients without depression than in the controls. Urine iron was also significantly higher in the PD patients without depression than in the controls. Serum copper was significantly lower in the PD patients with depression than in both the PD patients without depression and the controls. Conclusions Excessive intake of iron and accumulation of manganese seemed to be involved in the etiology of non-depressive PD. |
出版者: | The Fukushima Society of Medical Science |
出版者(異表記): | 福島医学会 |
本文の言語: | eng |
このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/371 |
本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/371/1/FksmJMedSci_59_p76.pdf |
ISSN: | 0016-2590 2185-4610 |
DOI: | 10.5387/fms.59.76 |
PubMed番号: | 24500382 |
関連ページ: | http://dx.doi.org/10.5387/fms.59.76 |
権利情報: | © 2013 The Fukushima Society of Medical Science |
出現コレクション: | Vol.59 (2013)
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