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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.59 (2013) >
Please use this identifier to cite or link to this item:
http://ir.fmu.ac.jp/dspace/handle/123456789/371
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| Title: | Heavy metals in blood and urine and its relation to depressive symptoms in Parkinson's disease patients |
| Authors: | Fukushima, Tetsuhito
Tan, Xiaodong
Luo, Yunwen
Wang, Puqing
Song, Jinhui
Kanda, Hideyuki
Hayakawa, Takehito
Kumagai, Tomohiro
Kakamu, Takeyasu
Tsuji, Masayoshi
Hidaka, Tomoo
Mori, Yayoi |
| Affiliation: | 衛生学・予防医学講座 |
| Source title: | Fukushima Journal of Medical Science |
| Volume: | 59 |
| Issue: | 2 |
| Start page: | 76 |
| End page: | 80 |
| Issue Date: | 2013 |
| Abstract: | Objectives Some heavy metals are suspected to be pathogenic to both Parkinson's disease (PD) and depression. Common background may exist in them. Methods Subjects comprised PD patients with depression, PD patients without depression and controls recruited from the outpatient clinic in China. Morning blood and urine samples were used to measure concentrations of metals and vitamins. Results Whole-blood manganese was significantly higher in the PD patients without depression than in both the PD patients with depression and the controls. Serum iron was significantly higher in the PD patients without depression than in the controls. Urine iron was also significantly higher in the PD patients without depression than in the controls. Serum copper was significantly lower in the PD patients with depression than in both the PD patients without depression and the controls. Conclusions Excessive intake of iron and accumulation of manganese seemed to be involved in the etiology of non-depressive PD. |
| Publisher: | The Fukushima Society of Medical Science |
| Publisher (Alternative foam): | 福島医学会 |
| language: | eng |
| URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/371 |
| Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/371/1/FksmJMedSci_59_p76.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.59.76 |
| PubMed ID: | 24500382 |
| Related Page: | http://dx.doi.org/10.5387/fms.59.76 |
| Rights: | © 2013 The Fukushima Society of Medical Science |
| Appears in Collections: | Vol.59 (2013)
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