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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.57 (2011) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/299
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| タイトル: | A challenge to appropriate antibiotic use in children with respiratory infections: a 5-year single-institution experience |
| その他のタイトル: | Treatment without antibiotics in children with cold |
| 著者: | Matsumoto, Ayumi
Hashimoto, Koichi
Kawasaki, Yukihiko
Hosoya, Mitsuaki |
| 学内所属: | 小児科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 57 |
| 号: | 2 |
| 開始ページ: | 33 |
| 終了ページ: | 45 |
| 発行日: | 2011年 |
| 抄録: | BACKGROUND: We have studied the rate of emergence of antibiotic-resistant Streptococcus pneumoniae (S. pneumoniae) and Haemophilus influenzae (H. influenzae) and the subsequent antibiotic use in host patients of those isolates at the Department of Pediatrics, Soma General Hospital, Fukushima. Moreover, we carried out several studies investigating the risks and benefits of antibiotic-free treatment for children with respiratory infections. In this report, we summarize our research and suggest better treatment options for pediatric patients with respiratory infections. METHODS: We investigated the necessity of antibiotic use in the treatment of pediatric inpatients with respiratory syncytial virus (RSV) infection, and tested our hypothesis that antibiotic-free treatment for common cold will reduce the number of resistant S. pneumoniae strains in the pediatric nasopharynx. Therefore, we restricted prescribing antibiotics for pediatric patients with respiratory infections. The rates of resistant S. pneumoniae and H. influenzae and the medication history of the host patients before and after the intervention were compared. RESULTS: We found that most of the RSV-infected patients recovered without antibiotic treatment, and that the antibiotic-free treatment inhibited the emergence of antibiotic-resistant strains. The rate of penicillin-resistant S. pneumoniae decreased but the rate of ampicillin-resistant H. influenzae did not change significantly during the study. CONCLUSION: We concluded that patients with respiratory infections can be treated without antibiotics, under careful examination and observation. Continued monitoring of such new interventions as well as recommending their use to other caregivers and physicians will help inhibit the spread of resistant strains. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/299 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/299/1/FksmJMedSci_57_p33.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.57.33 |
| PubMed番号: | 22353649 |
| 異版(出版者版等): | http://dx.doi.org/10.5387/fms.57.33 |
| 権利情報: | © 2011 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.57 (2011)
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