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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.56 (2010) >

このアイテムの引用には次の識別子を使用してください: http://ir.fmu.ac.jp/dspace/handle/123456789/276


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タイトル: A 10-year-old girl with IgA nephropathy who 5 years later developed the characteristic features of henoch-schönlein purpura nephritis
その他のタイトル: A girl with IgAN and HSPN
著者: Chishiki, Mina
Kawasaki, Yukihiko
Kaneko, Mariko
Ushijima, Yumiko
Ohara, Shinichiro
Abe, Yusaku
Suyama, Kazuhide
Hashimoto, Koichi
Hosoya, Mitsuaki
学内所属: 小児科学講座
誌名/書名: Fukushima Journal of Medical Science
巻: 56
号: 2
開始ページ: 157
終了ページ: 161
発行日: 2010年12月
抄録: We report a patient who developed Henoch-Schönlein purpura (HSP) 5 years after she presented with immunoglobulin A nephropathy (IgAN). A 10-year-old Japanese female was identified with proteinuria and hematuria by a school urinary screening. The first renal biopsy showed mesangial proliferative glomerulonephritis with immunofluorescent findings consistent with IgAN. She was treated with prednisolone, warfarin, and dilazep dihydrochloride, and the proteinuria and hematuria disappeared 4 months after the onset of treatment. Five years later she developed abdominal pain, gross hematuria and a classic purpuric rash of HSP after acute pharyngitis. The second renal biopsy showed diffuse mesangial proliferation with cellular crescent formation, and the patient was treated with methylprednisolone pulse therapy, prednisolone and mizoribine, resulting in a gradual decrease in urinary protein excretion. Our patient is unusual in that she developed Henoch-Schönlein purpura nephritis 5 years after clinical and biopsy evidence of IgAN, which suggests that IgAN and HSP are different clinical manifestations of the same disease, probably sharing a common pathogenesis.
出版者: The Fukushima Society of Medical Science
出版者(異表記): 福島医学会
本文の言語: eng
このページのURI: http://ir.fmu.ac.jp/dspace/handle/123456789/276
本文URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/276/1/FksmJMedSci_56_p157.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.56.157
PubMed番号: 21502718
異版(出版者版等): http://dx.doi.org/10.5387/fms.56.157
権利情報: © 2010 The Fukushima Society of Medical Science
出現コレクション:Vol.56 (2010)


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FksmJMedSci_56_p157.pdf406.26 kBAdobe PDFダウンロード



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