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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.56 (2010) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/275
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| タイトル: | A long-term remission of renal amyloidosis with nephrotic syndrome after autologous peripheral blood stem-cell transplantation |
| その他のタイトル: | Auto-PBSCT for renal amyloidosis |
| 著者: | Ogawa, Kazuei
Ikeda, Kazuhiko
Furukawa, Miki
Harada-Shirado, Kayo
Mashimo, Yumiko
Takahashi, Hiroshi
Matsumoto, Hayato
Kimura, Satoshi
Shichishima-Nakamura, Akiko
Ohkawara, Hiroshi
Hashimoto, Yuko
Asahi, Koichi
Noji, Hideyoshi
Ohto, Hitoshi
Takeishi, Yasuchika |
| 学内所属: | 循環器・血液内科学講座
輸血・移植免疫学講座
病理病態診断学講座
腎臓高血圧・糖尿病内分泌代謝内科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 56 |
| 号: | 2 |
| 開始ページ: | 151 |
| 終了ページ: | 156 |
| 発行日: | 2010年12月 |
| 抄録: | Renal amyloidosis is typically characterized by nephrotic syndrome, often with massive proteinuria and refractory peripheral edema. We report the case of a patient with renal amyloidosis associated with nephrotic syndrome who maintained remission for 6 years after undergoing high-dose chemotherapy followed by autologous peripheral blood stem-cell transplantation (auto-PBSCT). The patient was a man aged in his 50s who had developed nephrotic syndrome. Bone marrow aspiration and kidney biopsy determined that the cause of the nephrotic syndrome was renal amyloidosis due to multiple myeloma, and the patient was admitted to our department in July 2003. After one course of chemotherapy, auto-PBSCT was performed in March 2004. Following transplantation, serum M-protein was no longer detectable from March 2005, and the patient achieved complete hematological remission. Subsequently, proteinuria decreased, serum albumin levels normalized, and nephrotic syndrome improved. As of 6 years after transplantation, in March 2010, the patient remained in remission, meaning that auto-PBSCT proved extremely effective as a treatment for renal amyloidosis in this case. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/275 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/275/1/FksmJMedSci_56_p151.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.56.151 |
| PubMed番号: | 21502717 |
| 異版(出版者版等): | http://dx.doi.org/10.5387/fms.56.151 |
| 権利情報: | © 2010 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.56 (2010)
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