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Fukushima Journal of Medical Science >
Vol.56 (2010) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/270

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Title: Therapy-related myelodysplastic syndrome following cyclophosphamide pulse and/or methotrexate therapy in a patient with systemic lupus erythematosus.
Other Titles: Lupus nephritis and therapy-related myelodysplastic syndrome
Authors: Iwadate, Haruyo
Kobayashi, Hiroko
Yano, Kiori
Watanabe, Hiroshi
Ikeda, Kazuhiko
Ogawa, Kazuei
Ohira, Hiromasa
Affiliation: 消化器・リウマチ膠原病内科学講座
循環器・血液内科学講座
Source title: Fukushima Journal of Medical Science
Volume: 56
Issue: 2
Start page: 121
End page: 127
Issue Date: Dec-2010
Abstract: A 27-year-old woman exhibited progressive pancytopenia during cyclophosphamide pulse therapy for lupus nephritis and low-dose methotrexate therapy for severe arthralgia. Bone marrow aspiration revealed highly abnormal cell morphology, indicating therapy-related myelodysplastic syndrome. Pancytopenia and bone marrow cell morphology improved 3 months after discontinuation of cyclophosphamide. It is necessary to promptly examine bone marrow cell morphology and chromosomal aberration in cases with connective tissue diseases complicated by sudden cytopenia during immunosuppressive therapy with chemotherapeutic agents.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/270
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/270/1/FksmJMedSci_56_p121.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.56.121
PubMed ID: 21502712
Other version: http://dx.doi.org/10.5387/fms.56.121
Rights: © 2010 The Fukushima Society of Medical Science
Appears in Collections:Vol.56 (2010)

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FksmJMedSci_56_p121.pdf1.21 MBAdobe PDFDownload

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