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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.56 (2010) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/258
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| タイトル: | Non-antibiotic treatment for pediatric outpatients with common cold inhibits the emergence of drug resistant pneumococci |
| その他のタイトル: | Medicine without antibiotics to children with cold |
| 著者: | Matsumoto, Ayumi
Takeyama, Aya
Hashimoto, Koichi
Ito, Masaki
Katayose, Masahiko
Kato, Kazuo
Kawasaki, Yukihiko
Hosoya, Mitsuaki |
| 学内所属: | 小児科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 56 |
| 号: | 1 |
| 開始ページ: | 28 |
| 終了ページ: | 37 |
| 発行日: | 2010年6月 |
| 抄録: | The occurrence of drug resistant Streptococcus pneurmoniae (S. pneumoniae) is very high in Japan. Unnecessary use of antibiotics had been thought to cause this problem but previous studies had not clearly showed that the decreasing rate of antibiotic use had been related to the reduction of the prevalence of resistant strains. In this study, we tried to prove that non-antibiotic treatment for common cold would reduce the antibiotic resistant S. pneumoniae in nasopharynx in children. Forty-five children with the common cold were randomly selected from pediatric patients who had taken antibiotics within the past three months. We collected nasopharyngeal swabs from all of the participants and once again after a period of 2 to 3 months without using any antibiotics. Twenty-four of these patients had the S. pneumoniae strains isolated. Then these strains were undergone a susceptibility test and drug-resistant gene detection. The susceptibility test reveled that patients with penicillin-resistant strains decreased from 17 to 7 (p < 0.01). The test also reveled that the decreased number of patients had strains that were resistant to cefditren. The gene detection revealed that none of the patients acquired a higher resistance to penicillin. Our study suggests that the treatment without antibiotics reduces the drug-resistant S. pneumoniae. Controlled antibiotic use in children might prevent children from carrying the antibiotic resistant S. pneumoniae. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/258 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/258/1/FksmJMedSci_56_p28.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.56.28 |
| PubMed番号: | 21485653 |
| 異版(出版者版等): | http://dx.doi.org/10.5387/fms.56.28 |
| 権利情報: | © 2010 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.56 (2010)
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