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Vol.70 (2024) >

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Title: Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders
Authors: Suzuki, Yuichi
Itagaki, Shuntaro
Nodera, Maki
Suyama, Kazuhide
Yabe, Hirooki
Hosoya, Mitsuaki
Affiliation: 小児科学講座
Source title: Fukushima Journal of Medical Science
Volume: 70
Issue: 2
Start page: 75
End page: 85
Issue Date: 2024
Abstract: Background: This study investigated changes of lipid parameters in children with severe eating disorders during refeeding in order to explore the optimal timing for lipid preparation administration. Methods: We prospectively assessed the physical conditions of patients with eating disorders after the start of nutrition therapy. The assessments were performed at admission and at 2 and 4 weeks. Lipid metabolism was assessed based on triglyceride (TG), total cholesterol (TC), and free carnitine (FC) levels, as well as acylcarnitine/free carnitine (AC/FC) ratio. Results: A total of 18 patients were included. Of these, 12 and 6 received an oral diet (OD group) and total parenteral nutrition (TPN group), respectively. The mean body mass indexes at hospital admission were 12.8 kg/m2 in the OD group and 12.7 kg/m2 in the TPN group. At 2 weeks after the start of refeeding, TC, TG, and AC/FC levels were significantly lower in the TPN group than in the OD group. Other blood test results did not show any significant differences between the two groups. Conclusions: Fat-free glucose-based nutrition promoted lipid metabolism over a 2-week period after the start of refeeding, suggesting that balanced energy and lipid intake are essential, even in TPN.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/2233
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/2233/1/FksmJMedSci_70_p75.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.2023-02
PubMed ID: 38599829
Related Page: https://doi.org/10.5387/fms.2023-02
Rights: © 2024 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/
Appears in Collections:Vol.70 (2024)

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FksmJMedSci_70_p75.pdf2.11 MBAdobe PDFDownload

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