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Vol.54 (2008) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/222

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Title: Acute myocardial infarction in Fukushima area of Japan
Other Titles: AMI in Fukushima
Authors: Mitsugi, Minoru
Kijima, Mikihiro
Seino, Yoshitane
Abe, Yukihiko
Fujino, Akihisa
Hirosaka, Akira
Hisa, Shinichi
Kubo, Takaaki
Maeyama, Tadami
Ohara, Naoto
Ono, Masahiro
Owada, Takayuki
Saito, Tomiyoshi
Igarashi, Morio
Sato, Masahiko
Suzuki, Shigefumi
Tamagawa, Kazuaki
Tsuda, Tatsunori
Tsuda, Akihiro
Watanabe, Masayuki
Yui, Mitsuru
Komatsu, Nobuo
Nakazato, Kazuhiko
Maruyama, Yukio
Affiliation: 内科学第一講座
Source title: Fukushima Journal of Medical Science
Volume: 54
Issue: 1
Start page: 25
End page: 37
Issue Date: Jun-2008
Abstract: Although acute myocardial infarction (AMI) is the most serious coronary disease, the background of its onset and the mortality are not fully understood, especially in Japan. From June 1999 to May 2005, we mailed an annual questionnaire to eighteen hospitals in which emergency cardiac catheterization and percutaneous coronary intervention (PCI) were available in the Fukushima area of Japan. A total of 1,590 patients were included. The onset time of AMI had two peaks, i.e., from 9:00 AM to 10:00 AM and 9:00 PM to 10:00 PM. As for reperfusion therapy, four groups were analyzed, the non-reperfusion therapy group (Group N, n = 233), thrombolysis alone group (Group T, n = 80), PCI without thrombolysis group (Group P, n = 1106), and PCI with thrombolysis group (Group TP, n = 151). The in-hospital mortality rate was significantly reduced in Group P (8.4%) compared with that in Group N (33.0%, p < 0.01) and Group T (18.8%, p < 0.01). However, the in-hospital mortality in Group P did not differ from that in Group TP (9.9%). The in-hospital mortality was analyzed by the logistic regression analysis among age, arrival time after onset, peak creatine kinase (CK) values, coronary risk factors, reperfusion therapy, PCI, and thrombolysis. There were significant differences in age (P < 0.01), peak CK values (p < 0.01), hypertension (p < 0.05), and diabetes mellitus (p < 0.01). These results suggest that the onset of AMI may be partly related to human biorhythms, and that PCI would be effective in reducing the in-hospital mortality.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/222
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/222/1/FksmJMedSci_54_p25.pdf
ISSN: 0016-2590
PubMed ID: 18924550
Rights: © 2008 The Fukushima Society of Medical Science
Appears in Collections:Vol.54 (2008)

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