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Vol.69 (2023) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/2200

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Title: Cytokine profiles in an extremely preterm infant with congenital syphilis
Authors: Fukama, Eisuke
Nomura, Tomoaki
Hatanaka, Daisuke
Kusakari, Michiko
Takahashi, Hidehiro
Nakamura, Toshihiko
Takahashi, Naoto
Source title: Fukushima Journal of Medical Science
Volume: 69
Issue: 3
Start page: 185
End page: 189
Issue Date: 2023
Abstract: We report the cytokine profiles of an infant with congenital syphilis as a first case. This female infant was born by vaginal delivery at a gestational age of 27 weeks during her mother's treatment for syphilis. Elevation of T helper (Th)-1 cytokines (interleukin (IL)-2, IL-12) and IL-17, which supports immunological mechanisms of Th-1, was similar to that in cases of syphilis in adults. IL-6 and granulocyte colony-stimulating factor (G-CSF), the synergistic effects of which cause the leukemoid reaction, were also elevated. The levels of interferon-γ and IL-17 in cerebral spinal fluid, which are elevated in neurosyphilis in adults, were slightly elevated.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/2200
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/2200/1/FksmJMedSci_69_p185.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.2023-06
PubMed ID: 37766559
Related Page: https://doi.org/10.5387/fms.2023-06
Rights: © 2023 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/
Appears in Collections:Vol.69 (2023)

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FksmJMedSci_69_p185.pdf191.76 kBAdobe PDFDownload

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