福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.69 (2023) >
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http://ir.fmu.ac.jp/dspace/handle/123456789/1958
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Title: | Different prognostic outcomes in two cases of FDG-PET/CT-Positive and -negative cardiac angiosarcoma |
Authors: | Yamakuni, Ryo Ishii, Shiro Yamada, Shoki Hara, Junko Suenaga, Hiroki Sugawara, Shigeyasu Sekino, Hirofumi Yamaki, Takayoshi Ishida, Keiichi Hashimoto, Yuko Ito, Hiroshi |
Affiliation: | 放射線医学講座 病理病態診断学講座 循環器内科学講座 心臓血管外科学講座 |
Source title: | Fukushima Journal of Medical Science |
Volume: | 69 |
Issue: | 1 |
Start page: | 45 |
End page: | 49 |
Issue Date: | 2023 |
Abstract: | Cardiac angiosarcoma is a rare malignant tumor with a poor prognosis, characterized by the high uptake of 18F-fluorodeoxyglucose (FDG). This case report presents two cases of cardiac angiosarcoma with a marked difference in FDG uptake and prognosis.Case Summary:Case 1: A 40-year-old male presented with syncope. Ultrasound echocardiography demonstrated a cardiac tumor with a high uptake of 18F-FDG (maximum standardized uptake value=9.2). The patient underwent heart catheterization and tumor biopsy. The pathological result was high-grade angiosarcoma, and the MIB-1(Ki-67) proliferation index was approximately 20%. Systemic chemotherapy was administered; however, the patient died 2 years and 5 months after disease onset.Case 2: A 65-year-old female had a right atrial tumor incidentally diagnosed during routine ultrasound echocardiography. The tumor exhibited a low uptake of 18F-FDG (maximum standardized uptake value=1.8). Open heart surgery was performed, and the tumor was completely resected. Histological analysis revealed low-grade angiosarcoma, and the MIB-1(Ki-67) proliferation index was less than 5%. The patient was followed-up and had not relapsed 2 years after surgery.Conclusion: 18F-FDG uptake may reflect pathological tumor grade and prognosis in cardiac angiosarcoma. |
Publisher: | The Fukushima Society of Medical Science |
Publisher (Alternative foam): | 福島医学会 |
language: | eng |
URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/1958 |
Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/1958/1/FksmJMedSci_69_p45.pdf |
ISSN: | 0016-2590 2185-4610 |
DOI: | 10.5387/fms.2022-13 |
PubMed ID: | 36775315 |
Related Page: | https://doi.org/10.5387/fms.2022-13 |
Rights: | © 2023 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
Rights: | https://creativecommons.org/licenses/by-nc-sa/4.0/ |
Appears in Collections: | Vol.69 (2023)
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