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Vol.69 (2023) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/1958

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Title: Different prognostic outcomes in two cases of FDG-PET/CT-Positive and -negative cardiac angiosarcoma
Authors: Yamakuni, Ryo
Ishii, Shiro
Yamada, Shoki
Hara, Junko
Suenaga, Hiroki
Sugawara, Shigeyasu
Sekino, Hirofumi
Yamaki, Takayoshi
Ishida, Keiichi
Hashimoto, Yuko
Ito, Hiroshi
Affiliation: 放射線医学講座
病理病態診断学講座
循環器内科学講座
心臓血管外科学講座
Source title: Fukushima Journal of Medical Science
Volume: 69
Issue: 1
Start page: 45
End page: 49
Issue Date: 2023
Abstract: Cardiac angiosarcoma is a rare malignant tumor with a poor prognosis, characterized by the high uptake of 18F-fluorodeoxyglucose (FDG). This case report presents two cases of cardiac angiosarcoma with a marked difference in FDG uptake and prognosis.Case Summary:Case 1: A 40-year-old male presented with syncope. Ultrasound echocardiography demonstrated a cardiac tumor with a high uptake of 18F-FDG (maximum standardized uptake value=9.2). The patient underwent heart catheterization and tumor biopsy. The pathological result was high-grade angiosarcoma, and the MIB-1(Ki-67) proliferation index was approximately 20%. Systemic chemotherapy was administered; however, the patient died 2 years and 5 months after disease onset.Case 2: A 65-year-old female had a right atrial tumor incidentally diagnosed during routine ultrasound echocardiography. The tumor exhibited a low uptake of 18F-FDG (maximum standardized uptake value=1.8). Open heart surgery was performed, and the tumor was completely resected. Histological analysis revealed low-grade angiosarcoma, and the MIB-1(Ki-67) proliferation index was less than 5%. The patient was followed-up and had not relapsed 2 years after surgery.Conclusion: 18F-FDG uptake may reflect pathological tumor grade and prognosis in cardiac angiosarcoma.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/1958
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/1958/1/FksmJMedSci_69_p45.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.2022-13
PubMed ID: 36775315
Related Page: https://doi.org/10.5387/fms.2022-13
Rights: © 2023 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/
Appears in Collections:Vol.69 (2023)

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