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Vol.52 (2006) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/183

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Title: Serotonin syndrome caused by minimum doses of SSRIS in a patient with spinal cord injury
Other Titles: Serotonin syndrome in spinal cord injury
Authors: Satoh, Koichiro
Takano, Shizuko
Onogi, Takashi
Ohtsuki, Koji
Kobayashi, Toshio
Affiliation: 附属リハビリテーション研究所
薬理学講座
Source title: Fukushima Journal of Medical Science
Volume: 52
Issue: 1
Start page: 29
End page: 33
Issue Date: Jun-2006
Abstract: There have been only a few reports of serotonin syndrome developing after mono-therapy with a selective serotonin reuptake inhibitor (SSRI). We report a case of serotonin syndrome caused by long-term therapy with fluvoxamine prior to treatment with paroxetine. An 18-year-old man with spinal cord injury (SCI) at thoracic level 2-3 presented with onset of serotonin syndrome after taking fluvoxamine (50 mg per day) for 8 weeks prior to treatment with paroxetine (10 mg per day) for 6 days. He had confusion, agitation, severe headache, tachycardia (124 beats/minute), hypertension (165/118 mmHg), high fever (39.1 degrees C), and myoclonus. All of the symptoms disappeared within 24 hours after discontinuation of administration of paroxetine. This is an interesting case of serotonin syndrome that developed after minimum doses of single therapy with an SSRI in a patient with SCI.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/183
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/183/1/FksmJMedSci_52_p29.pdf
ISSN: 0016-2590
PubMed ID: 16995352
Rights: © 2006 The Fukushima Society of Medical Science
Appears in Collections:Vol.52 (2006)

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