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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.52 (2006) >
Please use this identifier to cite or link to this item:
http://ir.fmu.ac.jp/dspace/handle/123456789/183
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| Title: | Serotonin syndrome caused by minimum doses of SSRIS in a patient with spinal cord injury |
| Other Titles: | Serotonin syndrome in spinal cord injury |
| Authors: | Satoh, Koichiro
Takano, Shizuko
Onogi, Takashi
Ohtsuki, Koji
Kobayashi, Toshio |
| Affiliation: | 附属リハビリテーション研究所
薬理学講座 |
| Source title: | Fukushima Journal of Medical Science |
| Volume: | 52 |
| Issue: | 1 |
| Start page: | 29 |
| End page: | 33 |
| Issue Date: | Jun-2006 |
| Abstract: | There have been only a few reports of serotonin syndrome developing after mono-therapy with a selective serotonin reuptake inhibitor (SSRI). We report a case of serotonin syndrome caused by long-term therapy with fluvoxamine prior to treatment with paroxetine. An 18-year-old man with spinal cord injury (SCI) at thoracic level 2-3 presented with onset of serotonin syndrome after taking fluvoxamine (50 mg per day) for 8 weeks prior to treatment with paroxetine (10 mg per day) for 6 days. He had confusion, agitation, severe headache, tachycardia (124 beats/minute), hypertension (165/118 mmHg), high fever (39.1 degrees C), and myoclonus. All of the symptoms disappeared within 24 hours after discontinuation of administration of paroxetine. This is an interesting case of serotonin syndrome that developed after minimum doses of single therapy with an SSRI in a patient with SCI. |
| Publisher: | The Fukushima Society of Medical Science |
| Publisher (Alternative foam): | 福島医学会 |
| language: | eng |
| URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/183 |
| Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/183/1/FksmJMedSci_52_p29.pdf |
| ISSN: | 0016-2590 |
| DOI: | 10.5387/fms.52.29 |
| PubMed ID: | 16995352 |
| Related Page: | https://doi.org/10.5387/fms.52.29 |
| Rights: | © 2006 The Fukushima Society of Medical Science |
| Appears in Collections: | Vol.52 (2006)
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