DSpace Fukushima Medical University

福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.50 (2004) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/159

Files in This Item:

File Description SizeFormat
FksmJMedSci_50_p65.pdf1.54 MBAdobe PDFDownload
Title: Histological distribution and ultrastructural features of immunoreactive terminals against RT97, a monoclonal antibody to a 200 kD neurofilament, in the spinal dorsal horn of a rat
Other Titles: RT97 positive fibers in the spinal cord
Authors: Ishii, Maiko
Miyashita, Tomoko
Tsuchiya, Kaori
Ueda, Kouki
Umemura, Akira
Honda, Takashi
Affiliation: 医学部(学生)
解剖学第二講座
Source title: Fukushima Journal of Medical Science
Volume: 50
Issue: 2
Start page: 65
End page: 74
Issue Date: Dec-2004
Abstract: Localization and ultrastructural features of immunoreactive fibers and terminals against RT-97, a mouse monoclonal antibody that recognizes subunit of a 200-kD neurofilament, were examined in the spinal dorsal horn of adult rats. Under a light-microscope, many RT-97 immunoreactive fibers were detected in the dorsal root, collaterals of the dorsal root in the dorsal funiculus, and laminae III and IV in the dorsal horn. Few immunoreactive fibers were found in laminae I and II. Electron microscopic observation demonstrated that almost all RT-97 immunoreactive fibers in the dorsal root were myelinated, and unmyelinated fibers immunonegative. The immunoreactive fibers entered into the dorsal horn passing through the collaterals of the dorsal root along the superficial gray lamina. In the dorsal horn, these fibers ascended into and then terminated in lamina II. RT-97 immunoreactive central terminals were semicircular or ellipsoid in appearance and contained many flat-type presynaptic vesicles. Some terminals made synaptic contact with dendritic profiles in lamina II. Our present results indicate that RT-97 is a useful marker for ultrastructural examination of terminals served by non-nociceptive A-fibers.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/159
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/159/1/FksmJMedSci_50_p65.pdf
ISSN: 0016-2590
PubMed ID: 15779572
Rights: © 2004 The Fukushima Society of Medical Science
Appears in Collections:Vol.50 (2004)

Files in This Item:

File Description SizeFormat
FksmJMedSci_50_p65.pdf1.54 MBAdobe PDFDownload

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard