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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.50 (2004) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/159
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| タイトル: | Histological distribution and ultrastructural features of immunoreactive terminals against RT97, a monoclonal antibody to a 200 kD neurofilament, in the spinal dorsal horn of a rat |
| その他のタイトル: | RT97 positive fibers in the spinal cord |
| 著者: | Ishii, Maiko
Miyashita, Tomoko
Tsuchiya, Kaori
Ueda, Kouki
Umemura, Akira
Honda, Takashi |
| 学内所属: | 医学部（学生）
解剖学第二講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 50 |
| 号: | 2 |
| 開始ページ: | 65 |
| 終了ページ: | 74 |
| 発行日: | 2004年12月 |
| 抄録: | Localization and ultrastructural features of immunoreactive fibers and terminals against RT-97, a mouse monoclonal antibody that recognizes subunit of a 200-kD neurofilament, were examined in the spinal dorsal horn of adult rats. Under a light-microscope, many RT-97 immunoreactive fibers were detected in the dorsal root, collaterals of the dorsal root in the dorsal funiculus, and laminae III and IV in the dorsal horn. Few immunoreactive fibers were found in laminae I and II. Electron microscopic observation demonstrated that almost all RT-97 immunoreactive fibers in the dorsal root were myelinated, and unmyelinated fibers immunonegative. The immunoreactive fibers entered into the dorsal horn passing through the collaterals of the dorsal root along the superficial gray lamina. In the dorsal horn, these fibers ascended into and then terminated in lamina II. RT-97 immunoreactive central terminals were semicircular or ellipsoid in appearance and contained many flat-type presynaptic vesicles. Some terminals made synaptic contact with dendritic profiles in lamina II. Our present results indicate that RT-97 is a useful marker for ultrastructural examination of terminals served by non-nociceptive A-fibers. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/159 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/159/1/FksmJMedSci_50_p65.pdf |
| ISSN: | 0016-2590 |
| DOI: | 10.5387/fms.50.65 |
| PubMed番号: | 15779572 |
| 関連ページ: | https://doi.org/10.5387/fms.50.65 |
| 権利情報: | © 2004 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.50 (2004)
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