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Vol.50 (2004) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/156

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Title: Gene delivery into the chicken embryo by using replication-competent retroviral vectors
Other Titles: Retroviral gene delivery into the chick
Authors: Sato, Noboru
Affiliation: 解剖学第一講座
Source title: Fukushima Journal of Medical Science
Volume: 50
Issue: 2
Start page: 37
End page: 46
Issue Date: Dec-2004
Abstract: Rous sarcoma virus (RSV)-derived retroviral vectors have allowed for efficient gene transfer into the chicken embryo which is a classical model for studying vertebrate development. Current evidence reveals that this method can be used for regionally restricted expression, inducible expression, and for interfering with endogenous gene function, suggesting that gain-of-function and loss-of-function strategies for specific genes can be achieved spatially and temporally in the avian embryo. Thus, retroviral-mediated gene transfer into the chicken embryo coupled with a wide variety of strategies is now an important tool to address specific biological questions in the vertebrate.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/156
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/156/1/FksmJMedSci_50_p37.pdf
ISSN: 0016-2590
PubMed ID: 15779569
Rights: © 2004 The Fukushima Society of Medical Science
Appears in Collections:Vol.50 (2004)

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FksmJMedSci_50_p37.pdf1.16 MBAdobe PDFDownload

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