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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.50 (2004) >
Please use this identifier to cite or link to this item:
http://ir.fmu.ac.jp/dspace/handle/123456789/156
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| Title: | Gene delivery into the chicken embryo by using replication-competent retroviral vectors |
| Other Titles: | Retroviral gene delivery into the chick |
| Authors: | Sato, Noboru |
| Affiliation: | 解剖学第一講座 |
| Source title: | Fukushima Journal of Medical Science |
| Volume: | 50 |
| Issue: | 2 |
| Start page: | 37 |
| End page: | 46 |
| Issue Date: | Dec-2004 |
| Abstract: | Rous sarcoma virus (RSV)-derived retroviral vectors have allowed for efficient gene transfer into the chicken embryo which is a classical model for studying vertebrate development. Current evidence reveals that this method can be used for regionally restricted expression, inducible expression, and for interfering with endogenous gene function, suggesting that gain-of-function and loss-of-function strategies for specific genes can be achieved spatially and temporally in the avian embryo. Thus, retroviral-mediated gene transfer into the chicken embryo coupled with a wide variety of strategies is now an important tool to address specific biological questions in the vertebrate. |
| Publisher: | The Fukushima Society of Medical Science |
| Publisher (Alternative foam): | 福島医学会 |
| language: | eng |
| URI: | http://ir.fmu.ac.jp/dspace/handle/123456789/156 |
| Full text URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/156/1/FksmJMedSci_50_p37.pdf |
| ISSN: | 0016-2590 |
| DOI: | 10.5387/fms.50.37 |
| PubMed ID: | 15779569 |
| Related Page: | https://doi.org/10.5387/fms.50.37 |
| Rights: | © 2004 The Fukushima Society of Medical Science |
| Appears in Collections: | Vol.50 (2004)
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