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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.49 (2003) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/144
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| タイトル: | A survey of urinary hippuric acid and subjective symptoms among occupational low toluene exposed workers |
| その他のタイトル: | Assesment of low toluene exposure |
| 著者: | Tanaka, Kazuko
Maeda, Takafumi
Kobayashi, Toshio
Tanaka, Masatoshi
Fukushima, Tetsuhito |
| 学内所属: | 衛生学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 49 |
| 号: | 2 |
| 開始ページ: | 129 |
| 終了ページ: | 139 |
| 発行日: | 2003年12月 |
| 抄録: | Biological monitoring of toluene exposure by urinary hippuric acid determination and a subjective symptom survey by self-administered questionnaire were performed in 20 workers at low toluene exposure in factories to evaluate the health hazard including dysfunction of nervous system. Environmental monitoring was carried out using toluene gas detection tubes. Urine samples were collected three times a day in order to measure hippuric acid: first before the commencement of work, then at the end of forenoon work, and lastly at the end of afternoon work. Toluene vapor concentrations of throughout the workday ranged from 15.3 to 31.4 ppm. The urinary hippuric acid concentrations correlated with the toluene concentrations of ambient air (r = 0.58, p = 0.01). The subjective symptoms increased in close association with the exposure to toluene; the prevalence rate of subjective symptoms "during work" in the exposed group was 15 times higher than the rate of the non-exposed group (p < 0.0001). The prevalence rate of subjective symptoms "off-work" in the exposed group was 2.4 times higher than the rate of the non-exposed group (p < 0.0001), and also the prevalence rate of "nineteen symptoms off-work which are apparently related to central nervous system (CNS) and autonomic nervous system (ANS)" in the exposed group was 1.8 times higher than the rate of the non-exposed group (p < 0.05). From these results, these subjective symptoms, which have been believed to be complained in high organic solvent exposure should be reassessed and reconsidered in evaluating the nervous system dysfunction and local irritation in relatively low toluene exposed workers. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/144 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/144/1/FksmJMedSci_49_p129.pdf |
| ISSN: | 0016-2590 |
| DOI: | 10.5387/fms.49.129 |
| PubMed番号: | 15065639 |
| 関連ページ: | https://doi.org/10.5387/fms.49.129 |
| 権利情報: | © 2003 The Fukushima Society of Medical Science |
| 出現コレクション: | Vol.49 (2003)
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