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Vol.66 (2020) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/1357

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Title: Attempting to define sentinel node micrometastasis in oral squamous cell carcinoma
Authors: Matsuzuka, Takashi
Uemura, Hirokazu
Yoshimoto, Seiichi
Miura, Kouki
Shiotani, Akihiro
Sugasawa, Masashi
Homma, Akihiro
Yokoyama, Junkichi
Tsukahara, Kiyoaki
Yoshizaki, Tomokazu
Yatabe, Yasushi
Kobari, Takehiro
Kosuda, Shigeru
Murono, Shigeyuki
Hasegawa, Yasuhisa
Affiliation: 放射線医学県民健康管理センター
耳鼻咽喉科学講座
Source title: Fukushima Journal of Medical Science
Volume: 66
Issue: 3
Start page: 143
End page: 147
Issue Date: 2020
Abstract: OBJECTIVE:The aim of this supplemental study of a sentinel node (SN) biopsy (SNB) trial for oral squamous cell carcinoma (OSCC) was to assess the effectiveness in identifying micrometastasis and determining whether elective neck dissection (END) is necessary. MATERIALS AND METHODS:Twenty-three patients with pathologically positive SNs were included. The sizes of the metastatic lesions in positive SNs (SMSNs) were classified and the rates of occult metastasis of non-SNs were compared. RESULTS:The patients were divided according to the SMSN:<0.2 mm (group A, n=3);0.2 mm to <2.0 mm (group B, n=7);and ≥2.0 mm (group C, n=13). The rates of occult metastasis in groups A, B, and C were 0% (0/3), 14% (1/7) and 23% (3/13), respectively. CONCLUSION:Rare cancer cell distribution to nodes other than SNs was observed in the patients with SN metastatic lesions of at least smaller than 0.2 mm in size, suggesting the possibility of defining SN micrometastasis in N0 OSCC.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/1357
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/1357/1/FksmJMedSci_66_p143.pdf
ISSN: 0016-2590
2185-4610
DOI: 10.5387/fms.2020-17
PubMed ID: 33268599
Related Page: https://doi.org/10.5387/fms.2020-17
Rights: © 2020 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/
Appears in Collections:Vol.66 (2020)

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