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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.66 (2020) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/1310
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| タイトル: | Higher modified Glasgow Prognostic Score and multiple stapler firings for rectal transection are risk factors for anastomotic leakage after low anterior resection in rectal cancer |
| 著者: | Sakamoto, Wataru
Ohki, Shinji
Kikuchi, Tomohiro
Okayama, Hirokazu
Fujita, Shotaro
Endo, Hisahito
Saito, Motonobu
Saze, Zenichiro
Momma, Tomoyuki
Kono, Koji |
| 学内所属: | 消化管外科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 66 |
| 号: | 1 |
| 開始ページ: | 10 |
| 終了ページ: | 16 |
| 発行日: | 2020年 |
| 抄録: | Objective: Anastomotic leakage (AL) is one of the most devastating complications of rectal cancer surgery. Not only does AL result in reduced quality of life, extended hospitalization and impaired defecatory function, it also has a high local recurrence rate. In this study, we investigated risk factors for AL as it may help to decrease its occurrence and improve patient outcomes. Methods: This study was a retrospective, single-institution study of rectal cancer patients who underwent elective low anterior resection between April 2002 and February 2018 at Fukushima Medical University Hospital. Patients were divided into two groups according to the presence of AL. Patient-, tumor-, and surgery-related variables were examined using univariate and multivariate analyses. Results: One hundred sixty-one patients, average age 63.5±11.5 years, were enrolled in the study. The overall AL rate was 6.8% (11/161). In the univariate analysis, modified Glasgow Prognostic Score (mGPS)=2 (p=0.003), use of multiple staplers (≥3 firings) for rectal transection (p=0.001) and intraoperative bleeding (≥250 g) were significantly associated with AL incidence. Multivariate analysis identified that mGPS = 2 (odds ratio [OR]: 19.6, 95% confidence interval [CI]: 2.96-125.00, p=0.002) and multiple firings (OR: 18.19, CI: 2.31-111.11, p=0.002) were independent risk factors for AL. Conclusion: Higher mGPS score and multiple firings were independent risk factors for AL. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/1310 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/1310/1/FksmJMedSci_66_p10.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2019-17 |
| PubMed番号: | 32074522 |
| 関連ページ: | https://doi.org/10.5387/fms.2019-17 |
| 権利情報: | © 2020 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 権利情報: | https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| 出現コレクション: | Vol.66 (2020)
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