|
福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.66 (2020) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/1309
|
| タイトル: | Autoantibodies associated with neuropsychiatric systemic lupus erythematosus: the quest for symptom-specific biomarkers |
| 著者: | Sato, Shuzo
Temmoku, Jumpei
Fujita, Yuya
Yashiro-Furuya, Makiko
Matsuoka, Naoki
Asano, Tomoyuki
Kobayashi, Hiroko
Watanabe, Hiroshi
Migita, Kiyoshi |
| 学内所属: | リウマチ膠原病内科学講座 |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 66 |
| 号: | 1 |
| 開始ページ: | 1 |
| 終了ページ: | 9 |
| 発行日: | 2020年 |
| 抄録: | Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs, including the central nervous system. Neuropsychiatric SLE (NPSLE) is a severe and potentially fatal condition. Several factors including autoantibodies have been implicated in the pathogenesis of NPSLE. However, definitive biomarkers of NPSLE are yet to be identified owing to the complexity of this disease. This is a major barrier to accurate and timely diagnosis of NPSLE. Studies have identified several autoantibodies associated with NPSLE; some of these autoantibodies are well investigated and regarded as symptom-specific. In this review, we discuss recent advances in our understanding of the manifestations and pathogenesis of NPSLE. In addition, we describe representative symptom-specific autoantibodies that are considered to be closely associated with the pathogenesis of NPSLE. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/1309 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/1309/1/FksmJMedSci_66_p1.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2020-02 |
| PubMed番号: | 32173681 |
| 関連ページ: | https://doi.org/10.5387/fms.2020-02 |
| 権利情報: | © 2020 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 権利情報: | https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| 出現コレクション: | Vol.66 (2020)
|
このリポジトリに保管されているアイテムは、他に指定されている場合を除き、著作権により保護されています。
|
