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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.65 (2019) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/1059
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| タイトル: | Successful laparoscopic resection of virilizing ovarian steroid cell tumor, not otherwise specified, in a 22-year-old woman: a case report and evaluation of the steroidogenic pathway |
| 著者: | Matsukawa, Jun
Takahashi, Toshifumi
Hada, Yurika
Kameda, Wataru
Ota, Kuniaki
Fukase, Mika
Takahashi, Kyoko
Matsuo, Koki
Mizunuma, Hideki
Nagase, Satoru |
| 学内所属: | ふくしま子ども・女性医療支援センター |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 65 |
| 号: | 3 |
| 開始ページ: | 133 |
| 終了ページ: | 139 |
| 発行日: | 2019年 |
| 抄録: | Objective: Ovarian steroid cell tumor (SCT) is a rare tumor with steroid-producing ability. We report a 22-year-old woman with secondary amenorrhea and hirsutism caused by an ovarian SCT-not otherwise specified (NOS), who underwent successfully laparoscopic resection of the tumor. Case report: A 22-year-old null gravida woman presented to a hospital, having amenorrhea for 18 months and increasing facial hair. Physical examination revealed obesity (body mass index, 37.3 kg/m2) with evident facial and trunk hair. Total and free serum testosterone, and dehydroepiandrosterone sulfate levels were found to be elevated. Levels of serum adrenocorticotropic hormone, gonadotropins, cortisol, aldosterone, and ovarian steroids were observed to be within reference intervals. Although polycystic ovaries were not found, a hyperechogenic solid tumor (3 cm) was detected on transvaginal ultrasonography. Laparoscopic resection of the tumor was performed. One month post-surgery, total and free testosterone levels were observed to have decreased, and menstruation resumed two months thereafter. The patient was histologically diagnosed with ovarian SCT-NOS. Expression of ovarian steroidogenic enzymes, which are related to hyperandrogenism, was observed. No disease recurrence has been reported for more than 5 years post-surgery. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/1059 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/1059/1/FksmJMedSci_65_p133.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2019-25 |
| PubMed番号: | 31827013 |
| 関連ページ: | https://doi.org/10.5387/fms.2019-25 |
| 権利情報: | © 2019 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 権利情報: | https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| 出現コレクション: | Vol.65 (2019)
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