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福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.65 (2019) >
このアイテムの引用には次の識別子を使用してください:
http://ir.fmu.ac.jp/dspace/handle/123456789/1054
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| タイトル: | Cryptorchidism after the Fukushima Daiichi Nuclear Power Plant accident:causation or coincidence? |
| 著者: | Kojima, Yoshiyuki
Yokoya, Susumu
Kurita, Noriaki
Idaka, Takayuki
Ishikawa, Tetsuo
Tanaka, Hideaki
Ezawa, Yoshiko
Ohto, Hitoshi |
| 学内所属: | 泌尿器科学講座
甲状腺・内分泌診療センター
臨床研究教育推進部
臨床研究イノベーションセンター
臨床研究センター
放射線物理化学講座
小児外科
医事課
放射線医学県民健康管理センター |
| 誌名/書名: | Fukushima Journal of Medical Science |
| 巻: | 65 |
| 号: | 3 |
| 開始ページ: | 76 |
| 終了ページ: | 98 |
| 発行日: | 2019年 |
| 抄録: | Cryptorchidism (undescended testes) is among the most common congenital diseases in male children. Although many factors have been linked to the incidence of cryptorchidism, and testicular androgen plays a key role in its pathogenesis, the cause remains unknown in most cases. Recently, a Japanese group published a speculative paper entitled, "Nationwide increase in cryptorchidism after the Fukushima nuclear accident." Although the authors implicated radionuclides emitted from the Fukushima accident as contributing to an increased incidence of cryptorchidism, they failed to establish biological plausibility for their hypothesis, and glossed over an abundance of evidence and expert opinion to the contrary. We assessed the adequacy of their study in terms of design setting, data analysis, and its conclusion from various perspectives. Numerous factors must be considered, including genetic, environmental, maternal/fetal, and social factors associated with the reporting of cryptorchidism. Other investigators have established that the doses of external and internal radiation exposure in both Fukushima prefecture and the whole of Japan after the accident are too low to affect testicular descent during fetal periods;thus, a putative association can be theoretically and empirically rejected. Alternative explanations exist for the reported estimates of increased cryptorchidism surgeries in the years following Japan's 2011 earthquake, tsunami, and nuclear crisis. Data from independent sources cast doubt on the extent to which cryptorchidism increased, if at all. In any case, evidence that radionuclides from the Fukushima Daiichi Nuclear Power Plant could cause cryptorchidism is lacking. |
| 出版者: | The Fukushima Society of Medical Science |
| 出版者（異表記）: | 福島医学会 |
| 本文の言語: | eng |
| このページのURI: | http://ir.fmu.ac.jp/dspace/handle/123456789/1054 |
| 本文URL: | http://ir.fmu.ac.jp/dspace/bitstream/123456789/1054/1/FksmJMedSci_65_p76.pdf |
| ISSN: | 0016-2590
2185-4610 |
| DOI: | 10.5387/fms.2019-22 |
| PubMed番号: | 31915325 |
| 関連ページ: | https://doi.org/10.5387/fms.2019-22 |
| 権利情報: | © 2019 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 権利情報: | https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| 出現コレクション: | Vol.65 (2019)
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