DSpace Fukushima Medical University

福島県立医科大学学術成果リポジトリ = Fukushima Medical University Repository >
福島医学会 = The Fukushima Society of Medical Science >
Fukushima Journal of Medical Science >
Vol.65 (2019) >

Please use this identifier to cite or link to this item: http://ir.fmu.ac.jp/dspace/handle/123456789/1002

Files in This Item:

File Description SizeFormat
FksmJMedSci_65_p50.pdf284.33 kBAdobe PDFDownload
Title: A male preterm infant with cow's milk allergy to human milk fortifier showing only severe respiratory symptoms
Authors: Nakamura, Toshihiko
Hatanaka, Daisuke
Kashima, Kohei
Kusakari, Michiko
Takahashi, Hidehiro
Kamohara, Takashi
Takahashi, Naoto
Source title: Fukushima Journal of Medical Science
Volume: 65
Issue: 2
Start page: 50
End page: 54
Issue Date: 2019
Abstract: We report a male infant with a birthweight of 1,400 g at 29 weeks 2 days gestation diagnosed as having cow's milk allergy (CMA) due to human milk fortifier, who developed severe respiratory symptoms. The infant had no gastrointestinal symptoms; rather, the initial symptoms were apnea attacks and wheezing with a prolonged expiratory phase that progressed to severe ventilatory insufficiency requiring mechanical ventilation. Aggravation of his general condition, which appeared to be due to sepsis, was improved by temporary starvation and respiratory care, but he relapsed on the resumption of enteral feeding of his mother's milk with a human milk fortifier. As a result, this event was interpreted as a positive oral food challenge test. The infant resumed complete breastfeeding without the fortifier and has not relapsed since. Examination of his serial cytokine profiles from residual serum revealed that although interleukin-5 was not increased, interferon (IFN)-γ was increased, suggesting some relation between the time course of IFN-γ and the infant's eosinophil count. These findings may indicate that the involvement of IFN-γ is one cause of the onset of this disease.
Publisher: The Fukushima Society of Medical Science
Publisher (Alternative foam): 福島医学会
language: eng
URI: http://ir.fmu.ac.jp/dspace/handle/123456789/1002
Full text URL: http://ir.fmu.ac.jp/dspace/bitstream/123456789/1002/1/FksmJMedSci_65_p50.pdf
ISSN: 0016-2590
DOI: 10.5387/fms.2019-10
PubMed ID: 31327804
Related Page: https://doi.org/10.5387/fms.2019-10
Rights: © 2019 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0/
Appears in Collections:Vol.65 (2019)

Files in This Item:

File Description SizeFormat
FksmJMedSci_65_p50.pdf284.33 kBAdobe PDFDownload

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard